Other reasons may be when you run Outlook in the compatibility mode, or if you are using a profile created in an older Outlook version, or if the Outlook data file (.pst or. No one knows the exact reason why this happens, but all versions of Microsoft Outlook from 2003 to the newest Outlook 2019 may be affected.
A good indication that the file is corrupted is when its size is 0 KB.
The main symptom of this problem is very obvious and easily recognizable: you click Outlook's icon, an hourglass appears and is hanging for a while, and then you get the "Cannot start Microsoft Office Outlook" error.Īccording to Microsoft, the major cause of this issue is a corrupted Navigation Pane settings file - profilename.xml, where "profilename" is the name of your Outlook profile. "Unable to start Microsoft Outlook" error - causes and symptoms
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